Chapter 57: The Adrenal Glands and other Abdominal Endocrine Disorders

A 42-year-old man presents with intermittent tachycardia and panic attacks. A computed tomography (CT) scan reveals a 4.5-cm mass at the right renal hilum and metastatic disease in the liver. The most likely underlying genetic mutation is in which gene?

A 64-year-old woman presents with flushing, wheeze and abdominal pain. A computed tomography (CT) scan reveals a mesenteric mass near the terminal ileum and two liver metastases. She is evaluated for a right hemicolectomy followed by liver resection. What is the most appropriate preoperative investigation?

A 35-year-old woman presents with severe resistant hypertension and mild hypokalaemia that resolves with potassium supplementation. Plasma aldosterone is markedly raised and the plasma renin activity is suppressed (plasma aldosterone/renin ratio = 3000). A computed tomography (CT) scan demonstrates a 15-mm lesion in the left adrenal gland whereas the right adrenal gland is normal. The next appropriate step is …

A 45-year-old woman presents with abdominal striae, easy bruising and difficulty standing up from a chair. An overnight dexamethasone suppression test (ODST) reveals a serum cortisol level of 400 nmol/L and late night salivary cortisol is raised. The next most important test is …

A 40-year-old man presents with repeated bouts of feeling faint. His symptoms are relieved by eating. He has noticed that he has gained weight over the last 6–12 months. The most appropriate investigation is …